Thursday, 30 July 2020

WHY DO WE GET GOOSE BUMPS?? EXPLORING THE SCIENCE BEHIND IT!!!


Lots of things can make our hair stand on end, from a cool breeze tickling our neck to a sense of impending danger. We might also experience goosebumps when we hear an inspirational speech or song. Some unrelated events elicit goosebumps. The reason for this is the physiology of emotions!
Centuries ago, people believed that goosebumps made our hair grow faster. Today, we know this is not the case, but goosebumps still hold some mystery.
When we’re cold, or we experience a strong emotion, such as fear, shock, anxiety, sexual arousal or even inspiration, goosebumps can suddenly pop up all over the skin.
Goosebumps occur when the arrector pili muscles cause the hairs to stand up, making the skin look bumpy. The arrector pili are smooth, involuntary muscles that a person cannot voluntarily contract. Hence, people cannot voluntarily cause their goosebumps. When the hairs stand up on the skin, it is known as piloerection. Goosebumps are an involuntary reaction to certain kinds of stimulation.
In a new study, Harvard University scientists have discovered the reason: the cell types that cause goosebumps are also important for regulating the stem cells that regenerate the hair follicle and hair. Underneath the skin, the muscle that contracts to create goosebumps is necessary to bridge the sympathetic nerve's connection to hair follicle stem cells. The sympathetic nerve reacts to cold by contracting the muscle and causing goosebumps in the short term, and by driving hair follicle stem cell activation and new hair growth over the long term.
Published in the journal Cell, these findings in mice give researchers a better understanding of how different cell types interact to link stem cell activity with changes in the outside environment.

These bumps are caused by a contraction of miniature muscles that are attached to each hair. Each contracting muscle creates a shallow depression on the skin surface, which causes the surrounding area to protrude. The contraction also causes the hair to stand up whenever the body feels cold. In animals with a thick hair coat, this rising of hair expands the layer of air that serves as insulation. The thicker the hair layer, the more heat is retained. In people, this reaction is useless because we do not have a hair coat, but goosebumps persist nevertheless.


The medical terms for goosebumps are piloerection, cutis anserina, and horripilation. The term “goosebumps” is most widely used because it’s easy to remember: The little bumps that form on your skin when this phenomenon happens.
The presence of goosebumps with piloerection on the skin tends to suggest that a person is cold, scared, or having an emotionally intense experience. Neurological, endocrine, or other systemic issues may cause this symptom, so people should see a doctor for any unusual or worrisome goosebumps.                  
In addition to cold, the hair will also stand up in many animals when they feel threatened--in a cat being attacked by a dog, for example. The elevated hair, together with the arched back and the sideward position the animal often assumes, makes the cat appear bigger in an attempt to make the dog back off.

People also tend to experience goosebumps during emotional situations, such as walking down the aisle during their wedding, standing on a podium and listening to a national anthem after winning in sports or even just watching horror movies on television. Quite often a person may get goosebumps many years after a significant event, just by thinking about the emotions she once experienced, perhaps while listening to the romantic song to which she danced many years ago with the love of her life.                           

The reason for all these responses is the subconscious release of a stress hormone called adrenaline. Adrenaline, which in humans is produced in two small beanlike glands that sit atop the kidneys, not only causes the contraction of skin muscles but also influences many other body reactions. In animals, this hormone is released when the animal is cold or facing a stressful situation, preparing the animal for a flight-or-fight reaction. In humans, adrenaline is often released when we feel cold or afraid, but also if we are under stress and feel strong emotions, such as anger or excitement. Other signs of adrenaline release include tears, sweaty palms, trembling hands, an increase in blood pressure, a racing heart or the feeling of 'butterflies' in the stomach.
Factors trigger goosebumps
Goosebumps appear when the arrector pili muscles contract, pulling the hairs into an upright position. On areas of the body that do not have much hair or that only have light hair, a person might notice only the erect hair follicle and not the hair itself. Erect hair follicles look swollen and slightly bigger than usual. This enables them to hold the hair upright, and it also causes goosebumps. A number of specific factors can give rise to goosebumps. These include;
Extreme temperatures: Chills and cold: Goosebumps play an essential role in the body’s ability to regulate its temperature. Other mammals, including humans’ primate ancestors, have thick hair that keeps them warm. When the hair stands up, it offers more insulation.
Many people notice goosebumps when they are cold. They may also appear when someone thinks about being cold, such as when they witness a cold scene in a movie. Some people also get goosebumps when they have chills that they associate with an illness or fever. Goosebumps can be experienced in the presence of flash-cold temperatures, for example, being in a cold environment, and the skin being able to re-balance its surface temperature quickly. The stimulus of cold surroundings causes the tiny muscles attached to each hair follicle to contract. This contraction causes the hair strands to stand straight, the purpose of which is to aid in quicker drying via evaporation of water clinging to the hair which is moved upward and away from the skin.

Emotionally intense experiencesSome emotionally intense experiences cause the body to release certain chemicals that can trigger goosebumps.
In an extremely stressful situation, the body can employ the "fight or flight" response. As the body prepares itself for either fighting or running, the sympathetic nervous system floods the blood with adrenaline (epinephrine), a hormone that speeds up heart rate, metabolism, and body temperature in the presence of extreme stress. Then the sympathetic nervous system also causes the piloerection reflex, which makes the muscles attached to the base of each hair follicle contract and forces the hair up. Likewise, intensely pleasurable experiences, such as listening to music or the gentle touch of a loved one, can cause the brain to release dopamine. Dopamine is a chemical that plays a role in motivation, reward, and pleasure. Experiences such as this can also cause goosebumps.
Music: Canadian researchers have suggested that when humans are moved by music their brains behave as if reacting to delicious food, psychoactive drugs, or money. The pleasure experience is driven by the chemical dopamine, which produces physical effects known as "chills" that cause changes in heart rate, breathing, temperature and the skin's electrical conductance. The responses correlate with the degree to which people rate the "pleasurability" of music. Dopamine release is greatest when listeners had a strong emotional response to music. "If music-induced emotional states can lead to dopamine release, as our findings indicate, it may begin to explain why musical experiences are so valued,” wrote the scientists
Ingestion: Medications and herbal supplements that affect body temperature and blood flow may cause piloerection. For example, one of the commonly reported side effects of the intake of yohimbine is piloerection.

Drugs: Certain drugs may also cause goosebumps. For example, a 2016 study identified two sisters who experienced goosebumps after taking a medication called milnacipran hydrochloride. Taking drugs that stimulate activity similar to those chemicals in the body that normally cause goosebumps may also trigger the phenomenon. For example, a person experiencing an adrenaline-like rush when using methamphetamine may also have goosebumps. Withdrawal from some drugs, such as opioids, may also cause goosebump.
Opiate withdrawal: Piloerection is one of the signs of opioid withdrawal. The term "cold turkey" meaning an abrupt withdrawal from a drug, may derive from the goosebumps that occur during abrupt withdrawal from opioids; this resembles the skin of a refrigerated plucked turkey.
Voluntary control: Scientists generally agree that, in normal circumstances, goosebumps are involuntary. This is because the arrector pili muscles, which cause goosebumps, are smooth muscles. People cannot typically control smooth muscles, unlike skeletal muscles, which they voluntarily use, for example, to move their legs and flex their arms. However, there is some limited evidence to suggest that a small number of people may be able to exert control over the arrector pili muscles. This enables them to trigger goosebumps voluntarily. A 2018 analysis details a few cases of people who supposedly have control over their goosebump reaction. It seemed that none of the people with this ability learned it via conditioning or training, and doctors do not know what causes it.
Post-mortem goosebumps: After a person dies, the chemical adenosine triphosphate, which provides the energy to cells, depletes, and lactate builds up in the muscles. This process causes the muscles to stiffen, thereby triggering rigour mortis. As part of rigour mortis, the arrector pili muscles also stiffen, giving rise to goosebumps, in most cases, goosebumps are nothing more than a temporary nuisance. However, goosebumps can be a sign of a long-lasting or serious medical condition. For example, goosebumps can also be a sign of:

Keratosis pilaris: A harmless and common skin condition that creates the look of goosebumps on the skin for long periods of time.
Autonomic dysreflexia: An overreaction of the nervous system caused by a spinal cord injury.
Temporal lobe epilepsy: A chronic seizure disorder.
Chills: For example, those associated with fevers caused by influenza.
Goosebumps are not a medical disease. They do not require treatment, and no treatment can completely prevent a person from getting goosebumps. That said, people who feel self-conscious about goosebumps or want to avoid them can reduce their frequency by wearing warm clothing, especially when it is cool outside, avoiding drafts and heavy air conditioning, remaining calm during stressful or emotionally intense situations, avoiding illegal drugs. The right treatment can help manage the symptoms of keratosis pilaris. Some strategies that may help include: regularly moisturizing the skin with thick moisturizing cream, using chemical exfoliators, such as lactic acid or salicylic acid, to remove dead skin, trying laser treatment, if other strategies do not work.


Ms. Aleesha R, M. Pharm, Asst. Professor,
Dept. of Pharmacology, Nirmala College of Pharmacy, Muvattupuzha

1 comment:

  1. Thank you Aleesha miss for revealing the mystery behind goosebumps..

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